Ankylosing Spondylitis
What it is?
Causes
AS commonly manifests during early adulthood, usually in the late teens or twenties, and predominantly affects men. The exact cause is unknown, but it is believed to have a genetic component, as the human leukocyte antigen B27 (HLA-B27) gene is present in a majority of individuals with AS.
The inflammation associated with AS gradually leads to the fusion of affected vertebrae, resulting in a rigid and immobile spine. This fusion can also occur in other joints, such as the hips and shoulders, causing further limitations in mobility.
Symptoms
Diagnosis
Diagnosis of AS involves a combination of evaluating symptoms, physical examination, and medical imaging (such as X-rays or magnetic resonance imaging) to assess joint damage and inflammation. Blood tests may also be performed to check for the presence of HLA-B27 gene.
While there is no cure for AS, treatment aims to alleviate symptoms, slow down the progression of the disease, and maintain functionality. Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed to manage pain and reduce inflammation. Physical therapy and regular exercise can help improve range of motion and strengthen affected joints. In severe cases, biologic medications, such as tumor necrosis factor (TNF) inhibitors, may be used to slow disease progression.
Living with AS requires ongoing management and adapting to limitations caused by the disease. Regular exercise, practicing good posture, and maintaining a healthy weight are recommended to manage symptoms. Support from healthcare professionals, such as rheumatologists or physiotherapists, can also be beneficial in developing an individualized treatment plan.
Ankylosing Spondylitis
What it is?
Causes
AS commonly manifests during early adulthood, usually in the late teens or twenties, and predominantly affects men. The exact cause is unknown, but it is believed to have a genetic component, as the human leukocyte antigen B27 (HLA-B27) gene is present in a majority of individuals with AS.
The inflammation associated with AS gradually leads to the fusion of affected vertebrae, resulting in a rigid and immobile spine. This fusion can also occur in other joints, such as the hips and shoulders, causing further limitations in mobility.
Symptoms
Diagnosis
Diagnosis of AS involves a combination of evaluating symptoms, physical examination, and medical imaging (such as X-rays or magnetic resonance imaging) to assess joint damage and inflammation. Blood tests may also be performed to check for the presence of HLA-B27 gene.
While there is no cure for AS, treatment aims to alleviate symptoms, slow down the progression of the disease, and maintain functionality. Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed to manage pain and reduce inflammation. Physical therapy and regular exercise can help improve range of motion and strengthen affected joints. In severe cases, biologic medications, such as tumor necrosis factor (TNF) inhibitors, may be used to slow disease progression.
Living with AS requires ongoing management and adapting to limitations caused by the disease. Regular exercise, practicing good posture, and maintaining a healthy weight are recommended to manage symptoms. Support from healthcare professionals, such as rheumatologists or physiotherapists, can also be beneficial in developing an individualized treatment plan.
Patient Testimonials
Orthoderm brings a wealth of knowledge, a depth of understanding, and a shared commitment to patient-centered care.






I have recently got the knee surgery done for my mother. It was a complex surgery but it went very well. Thanks to Dr. Anish for being so supportive and making it easier for us. He is very humble, always very patient in addressing all the queries. He spends lot of time in explaining, providing every necessary details and ensuring the patient is ready and comfortable.
Manish Agrawal






Consulted him for my mother’s frozen shoulder. He gave her an injection which was completely painless and she instantly got relief. He took time to explain all the exercises and precautions. He listened to us patiently and gave answers to all possible questions. Highly recommended.
Karishma Konwar






Consulted sir for my mothers knee pain / osteoarthritis. Sir suggested PRP for my mother’s knee pain, we thought it would be painful. But there was no pain and only after 15 days of injection, she feels much better now.
Hirak Jyoti Sarmah






I have recently got the knee surgery done for my mother. It was a complex surgery but it went very well. Thanks to Dr. Anish for being so supportive and making it easier for us. He is very humble, always very patient in addressing all the queries. He spends lot of time in explaining, providing every necessary details and ensuring the patient is ready and comfortable.
Manish Agrawal






Consulted him for my mother’s frozen shoulder. He gave her an injection which was completely painless and she instantly got relief. He took time to explain all the exercises and precautions. He listened to us patiently and gave answers to all possible questions. Highly recommended.
Karishma Konwar
Contact Dr. Anish Agarwalla
Orthoderm brings a wealth of knowledge, a depth of understanding, and a shared commitment to patient-centered care.